FENTANYL OVERDOSE SYMPTOMS AND DURATION OPTIONS

Istradefylline forty mg/working day increased peak levels and AUC of CYP3A4 substrates in clinical trials. This effect was not observed with istradefylline 20 mg/day. Consider dose reduction of delicate CYP3A4 substrates.If coadministration of CYP3A4 inhibitors with fentanyl is essential, observe patients for respiratory depression and sedation at